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Dottoressa Chiara Lestuzzi

La Dott.ssa Chiara Lestuzzi è laureata in Medicina e Chirurgia (110/110 e lode) all'Università di Trieste nel 1979 con tirocinio pratico ospedaliero presso il Reparto di cardiologia dell'Ospedale di Udine (1980-81). Si è specializzata in Cardiologia (70/70) all'Università di Verona nel 1985.

Attività clinica

Si occupa di  cardiologia clinica con particolare interesse in ecocardiografia dal 1980, di patologie correlate ai tumori e alle terapie antineoplastiche dal 1981.

Principali campi di interesse e ricerca: cardiomiopatie, cardio-oncologia (tumori cardiaci primitivi e secondari, pericardite neoplastica, coinvolgimento cardiaco da tumori intratoracici), onco-cardiologia (cardiopatie post-radioterapiche, cardiotossicità da farmaci  antineoplastici), valvulopatie.

dal 01/01/2017
al 31/10/2022

Dirigente con incarico di Alta Specializzazione, AAS5 Friuli Occidentale, USD riabilitativa di Sacile (PN), sede di Aviano (PN)

da dic. 1999
al 31/12/2016

Dirigente con incarico di Alta Specializzazione di SOC Cardiologia, Centro di Riferimento Oncologico di Aviano

dal 1995
al 1999

Aiuto ospedaliero, UO Cardiologia, Ospedale di Portogruaro (VE)

dal 1986
al 1995

Assistente Ospedaliero, reparto di Cardiologia, Ospedale di Pordenone, con comando part-time di consulenza cardiologica al Centro di Riferimento Oncologico di Aviano

dal 1985
al 1986

Assistente ospedaliero, reparto di Medicina, Ospedale di Maniago (PN)

dal 1981
al 1985

Medico volontario presso il servizio di Emodinamica-Laboratorio di Ecocardiografia, Ospedale di Pordenone

1982

Medico supplente servizio di Medicina Scolastica, Pordenone

dal 1980
al 1985

Medico di Guardia Medica notturna e festiva, distretto di Codroipo

Attività associativa

Dal 2011

Associazione Patologia Cardiovascolare Italiana (APCI)

Dal 2011

Fellow Ecocardiochirurgia

Dal 2010

Membro del Working Group for Myocardial and pericardial disease dell'ESC

Dal 2010

Associazione Italiana di CardiOncologia (AICO)

Dal 2008

International Cardiooncology Society (ICOS)

Dal 1990

European Society of Cardiology

Dal 1982

Società Italiana di Ecografia Cardiovascolare (SIEC)

Dal 1981

Associazione Italiana Medici Cardiologi Ospedalieri (ANMCO)

Dal 2012

Fellow ANMCO

Dal 2015

Membro dell'Executive Committee for the Cardio Oncology Toxicity (COT) Registry dell'ESC

Dal 2016

Membro del consiglio direttivo del Collegio Federativo di Cardiologia (Italian Council of Cardiology Practice)

Dal 2018

Membrodell'European Council of Cardio-Oncology

       

Membro della Task Force di cardio-oncologia dell'ANMCO 

       

Membro dello Steering Committee dell'International Registry to Assess Cardiac Tumours (INTERACT)

       

Partecipazione allo studio BLITZ-AF CANCER della Fondazione Per il tuo Cuore/ANMCO, top 10 reclutatori 

Attività didattica e scientifica

Docente di Cardiologia alla Scuola per infermieri professionali, ospedale di Motta di Livenza (TV) (1986-1991)

Lezioni e letture magistrali presso la Scuola di Specializzazione in Oncologia dell'Università di Udine (2010-2019)

Corsi di Cardio-Oncologia organizzati da ARCA (Associazione Regionale Cardiologia Ambulatoriali) in Sicilia e Sardegna

Video lezioni per il corso "Continuità di cura in oncologia fra pazienti guariti e/o complessi: sostenibilità e social equity" organizzato da Unitelma Sapienza

Corso di Cardio-Oncologia per cardiologi ospedalieri dell'AAS5 Friuli Occidentale (2018)

Docente al master di 2° livello in Cure Palliative organizzato da UNIMI, Gargnano (BS) (20 maggio 2019)

Membro dell'Albo Docenti e Tutor dell'Azienda Sanitaria del Friuli Occidentale (ASFO): responsabile della formazione in Cardio-Oncologia (dal 2021)

Membro dell'Editorial Board di Journal of Clinical Ultrasound (dal 2021)

Guest Editor del topic Cardiac Tumors per Frontiers in Cardiovascular Medicine - section Cardio-Oncology

Letture, simposi e minimaster nei congressi dell'Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO). Letture a congressi dell'European Society of Cardiology (ESC)

Pubblicazioni

Lista non esaustiva delle pubblicazioni più significative in ambito scientifico.

Volumi

Lestuzzi C., Oliva S., Ferraù F., "Manual of Cardio-oncology: Cardiovascular Care in the Cancer Patient"

cover manual of cardio-oncology.tif

  1. Pino P, Moreo A, Lestuzzi C. Differential diagnosis of cardiac tumors. General consideration and echocardiographic approach. Journal of Clinical Ultrasound: Sonography and other Imaging Technique 2022 (in press)

  2. Cucciniello L, Bidoli E, Viel E, Canale ML, Lestuzzi C. The puzzling clinical presentation of fluoropyrimidines cardiotoxicity. Frontiers in Cardiovascular Medicine, Section Cardio-oncology. 2022 (in press)

  3. Lestuzzi C. Cardiac tumors: a diagnostic and therapeutic challenge. Editorial. Frontiers in cardiovascular medicine, Section Cardio-oncology. 2022 (in press)

  4. Tortorelli I, Navarria F, Di Maggio A, Banzato A, Lestuzzi C, Nicosia A, Chiusole I, Galiano A, Sbaraglia M, Zagonel V, Brunello A. Trabectedin and Radiation Therapy for Cardiac Metastasis From Leiomyosarcoma: A Case Report and Review of the Literature. Front. Oncol., 28 April 2022  

  5. Lestuzzi C,  Stolfo D, De Paoli A, Banzato A, Buonadonna A,  Bidoli,E,  Tartuferi,L,  Viel E, De Angelis G,  Lonardi S,  Innocente R, Berretta M,  Bergamo F,  Guglielmi A,  Sinagra G, Herrmann J. Cardiotoxicity from capecitabine chemotherapy: prospective study of incidence at rest and during physical exercise. The Oncologist 2022 Feb 16 e-Pub ahead of print

  6. Bisceglia I, Canale ML, Gallucci G, Turazza F, Lestuzzi C, et al.  Cardio-oncology in the COVID-19 era (CO&CO): The never ending story. (2022) Frontiers in Cardiovascular Medicine 2022 Jan 28;9:821193.

  7. Bisceglia I, Gabrielli D, Canale ML, Gallucci G, Parrini I, Turazza FM, Russo G, Maurea N, Quagliariello V, Lestuzzi C, Oliva S, Di Fusco SA, Lucà F, Tarantini L, Trambaiolo P, Gulizia MM, Colivicchi F. Position paper ANMCO: Cardio-oncologia in era COVID-19 [ANMCO Position paper: Cardio-oncology in the COVID-19 era]. G Ital Cardiol (Rome). 2021 Oct;22(10):800-825. Italian. doi: 10.1714/3666.36511. PMID: 34570114.

  8. Lestuzzi, C., Mascarin, M., Coassin, E., Canale, M. L., & Turazza, F. (2021). Cardiologic Long-Term Follow-Up of Patients Treated With Chest Radiotherapy: When and How?. Frontiers in cardiovascular medicine, 8, 671001. 

  9. Lestuzzi C. (2021). Impact of health insurance and socioeconomic status in the outcome of cancer and cardiac diseases. International journal of cardiology, 344, 184–185. 

  10. Canale, M. L., Turazza, F., Lestuzzi, C., Parrini, I., Camerini, A., Russo, G., Colivicchi, F., Gabrielli, D., Gulizia, M. M., Oliva, S., Tarantini, L., Maurea, N., Rigacci, L., Petrolati, S., Casolo, G., & Bisceglia, I. (2021). Portrait of Italian Cardio-Oncology: Results of a Nationwide Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) Survey. Frontiers in cardiovascular medicine, 8, 677544. https://doi.org/10.3389/fcvm.2021.677544

  11. Bisceglia, I., Gabrielli, D., Canale, M. L., Gallucci, G., Parrini, I., Turazza, F. M., Russo, G., Maurea, N., Quagliariello, V., Lestuzzi, C., Oliva, S., Di Fusco, S. A., Lucà, F., Tarantini, L., Trambaiolo, P., Gulizia, M. M., & Colivicchi, F. (2021). ANMCO POSITION PAPER: cardio-oncology in the COVID era (CO and CO). European heart journal supplements : journal of the European Society of Cardiology, 23(Suppl C), C128–C153. https://doi.org/10.1093/eurheartj/suab067

  12. Lestuzzi C, Miolo GM, Tartuferi L, et al. Ventricular arrhythmias due to glomangiosarcoma cardiac metastases. Case report and review of the literature. JACC: Cardio-Oncology 2021;3(1), 150–153.

  13. Lestuzzi C. Quali controlli cardiologici in corso di chemioterapia a rischio di cardiotossicità/Which cardiologic controls during chemotherapy at risk of cardiotoxicity. Cardiologia Ambulatoriale. 2020; 

  14. Gulizia M, Parrini i, Colivicchi F, Bisceglia I, ... Lestuzzi C,  et al. Consensus document of the Council of Cardiological Societies HCF-ANMCO / AICPR / GIEC / ITAHFA / SICOA / SICP / SIMG / SIT: Anticoagulant therapy in venous thromboembolism and atrial fibrillation of the patient with cancer. Current knowledge and new evidence. Giornale italiano di cardiologia 2020;  21: 687-738 

  15. Lestuzzi C, Reardon MJ. Primary Cardiac Malignancies: The Need for a Multidisciplinary Approach and the Role of the Cardio-Oncologist. J Am Coll Cardiol. 2020;75(18):2348-2351. Editorial

  16. Casavecchia G, Lestuzzi C, Gravina M, et al. Cardiac Tumors. J Cardiovasc Echogr. 2020;30(Suppl 1):S45-S53. 

  17. Maloberti, A, Palazzini, M.; Vallerio, P. Lestuzzi, C. Grasso, E. Sun, J.; Buono, A.; Sirico, D.; Giani, V.; Molinari, V; Biolcati, M.2; Lattuada, F.2; Pezzini, S.2; Moreo, A.1; Giannattasio, C. Radiotherapy as a risk factor for heart ischemia in subjects treated with chest irradiation and chemotherapy and without classic cardiovascular risk factors. Radiotherapy and Oncology. 2020 Nov;152:146-150.

  18. Lestuzzi C, Tartuferi L, Viel E, Buonadonna A, Vaccher E, Berretta M. Fluoropyrimidine-Associated Cardiotoxicity: Probably Not So Rare As It Seems [published online ahead of print, 2020 May 20]. Oncologist. 2020;10.1634/theoncologist.2020-0053

  19. Bisceglia I, Canale ML, Lestuzzi C, et al. Acute coronary syndromes in cancer patients [published online ahead of print, 2020 Jun 8]. J Cardiovasc Med (Hagerstown).

  20. Canale, M. L., Camerini, A., Casolo, G., Lilli, A., Bisceglia, I., Parrini, I., Lestuzzi, C., Del Meglio, J., Puccetti, C., Camerini, L., Amoroso, D., & Maurea, N. (2020). Incidence of Pericardial Effusion in Patients with Advanced Non-Small Cell Lung Cancer Receiving Immunotherapy. Adv Ther. 2020 Jul;37(7):3178-3184.

  21. Lestuzzi C, Annunziata MA, Nohria A, Muzzatti B, Bisceglia I, Ewer MS. Cancer patients in cardiology: how to communicate with patients with special psychological needs and manage their cardiac problems in daily clinical practice. J Cardiovasc Med (Hagerstown). 2020 Jan 20. 

  22. Canale ML, Bisceglia I, Lestuzzi C, Parrini I; ANMCO Cardio-Oncology Task Force. Arterial Thrombosis in Cancer: Spotlight on the Neglected Vessels. Anticancer Res. 2019 Sep;39(9):4619-4625.

  23. Canale ML, Camerini A, Huqi A, Lilli A, Bisceglia I, Parrini I, Lestuzzi C,Del Meglio J, Donati S, Venturini E, Sgambato A, Tarantini L, Amoroso D, Casolo G. Cardiovascular Risk Factors and Timing of Anthracyclines and Trastuzumab Cardiac Toxicity. Anticancer Res. 2019 Oct;39(10):5741-5745.

  24. Abrignani MG, Parrini I, Grosseto D, Lestuzzi C, Mistrangelo M, Passaretti B; a nome dell'Area Prevenzione Cardiovascolare ANMCO e della Task Force Cardioncologia ANMCO. [Lifestyle, risk factors and prevention of cancer: role of the cardiologist]. G Ital Cardiol (Rome). 2019 Jan;20(1):20-31. 

  25. Canale ML, Lestuzzi C, Bisceglia I, Valerio P, Parrini I. Cardio-Oncology organization patterns: one size does not fit all. Journal of Cardiovascular Medicine 2018, in press

  26. Lancellotti P,  Galderisi M, Donal E,  Edvardsen T,  Popescu BA, Farmakis D,  Filippatos D, Habib G,  Lestuzzi C,  Santoro C, Moonen M,  Jerusalem G, Anker SD.  Protocol update and preliminary results of EACVI/HFA Cardiac Oncology Toxicity (COT) Registry, of the European Society of Cardiology.  ESC Heart Fail. 2017 Aug;4(3):312-318

  27. Lestuzzi C, Berretta M, De Paoli A. Capecitabine cardiotoxicity: how to limit life-threatening events. International Journal of Cardiology, 2017 Feb 15;229:5.

  28. Lestuzzi C. Primary tumors of the heart. Curr Opin Cardiol. 2016;31:593-598. 

  29. Vallerio P, Sarno L, Stucchi M, Musca F, Casadei F, Maloberti A, Lestuzzi C, Mancia G, Moreo A, Palazzi M, Giannattasio C. Long-Term Effects of Radiotherapy on Arterial Stiffness in Breast Cancer Women. Am J Cardiol. 2016;118:771-6.

  30. Lestuzzi C, De Paoli A, Baresic T, Miolo GM, Buonadonna A. Malignant cardiac tumours; diagnosis and treatment. Future Cardiology 2015  Jul;11(4):485-500.

  31. Lestuzzi C, Tomkowski W, Berretta M. 2015 update on the diagnosis and management of neoplastic pericardial disease. Expert Opinion in Cardiology 2015 Apr;13(4):377-89.

  32. Fontanella C, Aita M, Cinausero M, Aprile G, Baldin MG, Dusi V, Lestuzzi C, Fasola G, Puglisi F. Capecitabine-induced cardiotoxicity: more evidence or clinical approaches to protect the patients' heart?" . OncoTargets and Therapy 2014; 7:1783-91.

  33. Celik S, Lestuzzi C, Cervesato E, Dequanter D, Piotti P, De Biasio M, Imazio M. Systemic chemotherapy in combination with pericardial window has better outcomes in malignant pericardial effusions. J Thorac Cardiovasc Surg. 2014 148(5):2288-93

  34. Lestuzzi C, Vaccher E, Talamini R, et al. Effort myocardial ischemia during chemotherapy with 5-Fluorouracil: an underestimated risk. Ann Oncol 2014 May;25(5):1059-64

  35. Russo G, Cioffi G, Gori S, Tuccia F, Boccardi L, Khoury G, Lestuzzi C, Maurea N, Oliva S, Faggiano P, Tarantini L; ICARO (Italian CARdio-Oncological) Network. Role of hypertension on new onset congestive heart failure in patients receiving trastuzumab therapy for breast cancer. J Cardiovasc Med (Hagerstown). 2014;15(2):141-6.

  36. Berretta M, Aprile G, Nasti G,Urbani M, Bearz A, Lestuzzi C, et al. Oxaliplatin and Capecitabine (XELOX) Based Chemotherapy in the Treatment of Metastatic Colorectal Cancer: The Right Choice in Elderly Patients. Anti-cancer Agents in Med Chem, 10/2013

  37. 37)  Imazio M, Belli R, Beqaraj F, Giammaria M, Lestuzzi C, Hoit B, Lewinter M, Spodick DH, Adler Y. DRainage Or Pericardiocentesis alone for recurrent nonmalignant, nonbacterial pericardial effusions requiring intervention: rationale and design of the DROP trial, a randomized, open-label, multicenter study. J Cardiovasc Med (Hagerstown). 2013 Jul 17.

  38. Lestuzzi C. Cardioncology, oncocardiology. Are we barking up the wrong tree?  International Journal of Cardiology 2013; 167: 307-309

  39. Tarantini L, Gori S, Faggiano P, Pulignano G, Simoncini E, Tuccia F,Ceccherini R, Bovelli D, Lestuzzi C, Cioffi G; ICARO (Italian CARdio-Oncologic) Network. Adjuvant trastuzumab cardiotoxicity in patients over 60 years of age with early breast cancer: a multicenter cohort analysis. Ann Oncol. 2012;23:3058-63

  40. Oliva S, Cioffi G, Frattini S, Simoncini EL, Faggiano P, Boccardi L, Pulignano G, Fioretti AM, Giotta F, Lestuzzi C, Maurea N, Sabatini S, Tarantini L; on behalf of the Italian Cardio-Oncological Network. Administration of Angiotensin-Converting Enzyme Inhibitors and β-Blockers During Adjuvant Trastuzumab Chemotherapy for Nonmetastatic Breast Cancer: Marker of Risk or Cardioprotection in the Real World? Oncologist. 2012 Jun 6. 

  41. Lestuzzi C, Spina M, Martellotta F, Carbone A. Massive cardiac infiltration by HIV-related non-Hodgkin lymphoma. J Cardiovasc Med 2012;13(12):836-8.

  42. Tarantini L, Cioffi G, Gori S, Tuccia F, Boccardi L, Bovelli D, Lestuzzi C,Maurea N, Oliva S, Russo G, Faggiano P; Italian Cardio-Oncologic Network. Trastuzumab adjuvant chemotherapy and cardiotoxicity in real-world women with breast cancer. J Card Fail. 2012 Feb;18(2):113-9.

  43. Lestuzzi C, Lafaras C, Tomkowski W, Imazio M, Moreo A, De Biasio M, Steffan A. Response to neoplastic Pericardial effusion. Clin Cardiol 2012; 34 (letter) 

  44. Berretta M, Zanet E, Nasti G, Lleshi A, Frustaci S, Fiorica F, Bearz A,Talamini R, Lestuzzi C, Lazzarini R, Fisichella R, Cannizzaro R, Iaffaioli RV,Berretta S, Tirelli U. Oxaliplatin-based chemotherapy in the treatment of elderly patients with metastatic colorectal cancer (CRC). Arch Gerontol Geriatr. 2011 Sep 19. PubMed PMID: 21937127.

  45. Lestuzzi C, Tartuferi L, Corona G. Capecitabine (and 5 Fluorouracil) Cardiotoxicity. Metabolic Considerations. Breast J. 2011;17(5):564-5;

  46.  Lestuzzi C. A case of multifactorial late left ventricular dysfunction after cancer treatment. Heart and Metabolism. 2011(51):31-3. 

  47. Lestuzzi C. Epidemiology, diagnosis and therapy of neoplastic pericarditis. Journal of Cardiovascular Echography. 2011;21(2):86-91. 

  48.  Boccardi L, Cardinale D, Civelli M, Lestuzzi C, Materazzo C, Maurea N, et al. Cardiological assessment in patients receiving cancer treatment. first document. Journal of Cardiovascular Echography. 2011;21(1):32-41. 

  49. Badano LP, Muraru D, Onut R, Lestuzzi C, Toso F. Three-dimensional imaging of  anomalous origin of the right coronary artery in a young athlete. Eur J Echocardiogr. 2011 Jun;12(6):481.

  50.  Lestuzzi C, Bearz A, Lafaras C, Gralec R, Cervesato E, Tomkowski W, et al. Neoplastic pericardial disease in lung cancer: Impact on outcomes of different treatment strategies. A multicenter study. Lung Cancer. 2011;72(3):340-7.

  51. Lestuzzi C. Neoplastic pericardial disease: Old and current strategies for diagnosis and management. World J Cardiol. 2010 Sep 26;2(9):270-9.

  52. Furlanello F, Serdoz LV, Botrè F, Accettura D, Lestuzzi C, De Ambroggi L,Cappato R. [Drugs and athletic activity: do they fit together?]. G Ital Cardiol (Rome). 2010 Oct;11(10 Suppl 1):118S-121S. Review. Italian.

  53. Imazio M, Brucato A, Mayosi BM, Derosa FG, Lestuzzi C, Macor A, et al. Medical therapy of pericardial diseases: Part II: Noninfectious pericarditis, pericardial effusion and constrictive pericarditis. J Cardiovasc Med. 2010;11(11):785-94.

  54. . Imazio M, Brucato A, Mayosi BM, Derosa FG, Lestuzzi C, Macor A, et al. Medical therapy of pericardial diseases: Part I: Idiopathic and infectious pericarditis. J Cardiovasc Med. 2010;11(10):712-22.

  55. . Furlanello F, Serdoz LV, Botrè F, Accettura D, Lestuzzi C, De Ambroggi L, et al. [Drugs and athletic activity: Do they fit together?]. Giornale italiano di cardiologia). 2010;11(10 Suppl 1):118S-21S.

  56. Furlanello, F., Botrè, F., Accettura, D., Cappato, R., De Ambroggi, L., Lestuzzi C,  et al. (2010). Pharmacological advice in sports cardiology. [Effetti cardiovascolari dei farmaci di interesse medico-sportivo] Medicina Dello Sport, 63(1), 127-136.

  57.  Lestuzzi C, Crivellari D, Rigo F, Viel E, Meneguzzo N. Capecitabine cardiac toxicity presenting as effort angina: A case report. J Cardiovasc Med. 2010;11(9):700-3.

  58. Lestuzzi C, Lafaras C, Bearz A, Gralec R, Viel E, Buonadonna A, et al. Malignant pericardial effusion: Sclerotherapy or local chemotherapy. Br J Cancer. 2009;101(4):734-5.

  59. Imazio M, Brucato A, DeRosa FG, Lestuzzi C, Bombana E, Scipione F, et al. Aetiological diagnosis in acute and recurrent pericarditis: When and how. J Cardiovasc Med. 2009;10(3):217-30.

  60.  Miolo G, La Mura N, Nigri P, Murrone A, Da Ronch L, Viel E, Lestuzzi C, et al. The cardiotoxicity of chemotherapy: New prospects for an old problem. Radiology and Oncology. 2006;40(3):149-61.

  61. Hrovatin E, Viel E, Lestuzzi C, Tartuferi L, Zardo F, Brieda M, et al. Severe ventricular dysrhythmias and silent ischemia during infusion of the antimetabolite 5-fluorouracil and cis-platin. J Cardiovasc Med. 2006;7(8):637-40.

  62. Crivellari D, Lombardi D, Corona G, Massacesi C, Talamini R, Sorio R, Lestuzzi C, et al. Innovative schedule of oral idarubicin in elderly patients with metastatic breast cancer: Comprehensive results of a phase II multi-institutional study with pharmacokinetic drug monitoring. Annals of Oncology. 2006;17(5):807-12.

  63. Hrovatin E, Zardo F, Brieda M, Dametto E, Piazza R, Antonini-Canterin F, et al. Prolonging QT interval and torsade de pointes in a patient with acquired human immunodeficiency virus in a multitherapy utilizing cytochrome P450. Italian Heart Journal, Supplementi. 2004;5(9):735-40.

  64. Lestuzzi C, Viel E, Picano E, Meneguzzo N. Coronary vasospasm as a cause of effort-related myocardial ischemia during low-dose chronic continuous infusion of 5-fluorouracil. Am J Med. 2001;111(4):316-8.

  65. Lestuzzi C, Viel E, Mimo R, Meneguzzo N. Left atrial invasion by lung carcinoma through a pulmonary vein. Int J Card Imaging. 2001;17(2):107-10.

  66. Lestuzzi C, Viel E, Sorio R, Meneguzzo N. Local chemotherapy for neoplastic pericardial effusion. Am J Cardiol.2000;86(11):1292.(letter)

  67. Viel E, Lestuzzi C, Badano LP, Canterin FA. Images in cardiovascular medicine: A malignant peripheral nerve sheath tumor presenting as an intrapericardial mass. Italian Heart Journal. 2000;1(6):438-9.

  68. De Cicco M, Macor F, Robieux I, Zanette G, Fantin D, Fabiani F, Lestuzzi C, et al. Pharmacokinetic and pharmacodynamic effects of high-dose continuous intravenous verapamil infusion: Clinical experience in the intensive care unit. Crit Care Med. 1999;27(2):332-9.

  69. Mocchegiani R, Badano L, Lestuzzi C, Nicolosi GL, Zanuttini D. Relation of right ventricular morphology and function in pectus excavatum to the severity of the chest wall deformity. Am J Cardiol. 1995;76(12):941-6.

  70. Lestuzzi C,  Nicolosi  GL; Viel M,  Zottarel G,  Sorio  R,  Calzavara G.   Cardiac toxicity of Interleukin-2 plus alfa-2 interferon.  Journal Am Coll  Cardiol  Special Issue: SI   Pages: A80-A80   Published: FEB 1994

  71.  Zottarel G, Nicolosi GL, Lestuzzi C, Zanuttini D. Normalization of left ventricular function and subsequent redilatation and pump failure in a patient with hypertensive heart disease in dilated phase after chemotherapy. G Ital Cardiol. 1994;24(7):869-75.

  72. Mocchegiani R, Lestuzzi C, Badano L, Nicolosi GL, Purcaro A, Zanuttini D. Right ventricular abnormalities mimicking right ventricular dysplasia in pectus excavatum. New Trends in Arrhythmias. 1993;9(4):1143-6.

  73.  Zanuttini D, Zardo F, Toffoli G, Lestuzzi C, Viel M, Nicolosi GL, et al. Cardiovascular effects of high-dose intravenous verapamil in neoplastic patients. New Trends in Arrhythmias. 1993;9(3):549-55.

  74. . Mimo R, Sparacino L, Nicolosi GL, Cervesato E, Wei DR, Grandis U, et al. Echocardiographic prediction of the final event in patients dying of acute myocardial infarction. Eur Heart J. 1993;14(6):775-9.

  75. Ren WD, Visentin P, Nicolosi GL, Canterin FA, Dall'Aglio V, Lestuzzi C, et al. Effect of atrial fibrillation on pulmonary venous flow patterns: Transoesophageal pulsed doppler echocardiographic study. Eur Heart J. 1993;14(10):1320-7.

  76. Engberding R, Daniel WG, Erbel R, Kasper W, Lestuzzi C, Curtius JM, et al. Diagnosis of heart tumours by transoesophageal echocardiography: A multicentre study in 154 patients. Eur Heart J. 1993;14(9):1223-8.

  77. Wei Dong Ren, Nicolosi GL, Lestuzzi C, Canterin FA, Golia P, Cervesato E, et al. Role of transesophageal echocardiography in evaluation of pulmonary venous obstruction by paracardiac neoplastic masses. Am J Cardiol. 1992;70(15):1362-6.

  78. Lestuzzi C, Nicolosi GL, Mimo R, Pavan D, Zanuttini D. Usefulness of transesophageal echocardiography in evaluation of paracardiac neoplastic masses. Am J Cardiol. 1992;70(2):247-51.

  79. Zanuttini D, Lestuzzi C, Nicolosi GL, Dall'Aglio V, Pavan D, Sparacino L. Right ventricular morphology and ventricular arrhythmias: Possible relationship in different cardiac abnormalities. New Trends in Arrhythmias. 1991;7(4):879-85.

  80. Lestuzzi C, Nicolosi GL, Neri A, Pavan D, Mimo R, Dall'Aglio V, et al. Familial dilated cardiomyopathy: A transverse and longitudinal clinical and echocardiographic study. Int J Cardiol. 1991;33(2):225-32.

  81. Mimo R, Sparacino L, Nicolosi GL, D'Angelo G, Dall'Aglio V, Lestuzzi C, et al. Quantification of mitral regurgitation: Comparison between transthoracic and transesophageal color doppler flow mapping. Echocardiography. 1991;8(6):619-26.

  82. Neri A, Lestuzzi C, Nicolosi GL. Evolving electrocardiographic changes in massive neoplastic infiltration of the right ventricle. description of a case and review of the literature. G Ital Cardiol. 1990;20(12):1182-6.

  83. Zanuttini D, Pignoni P, Nicolosi GL, Lestuzzi C, Burelli C, Bettini R, et al. Discrepancy between morpho-functional findings and clinical arrhythmias in right ventricular cardiomyopathy. New Trends in Arrhythmias. 1990;6(1-2):457-61.

  84. Nicolosi GL, Dall'Aglio V, Lestuzzi C, Mimo R, Pavan D, Zanuttini D. In: Overview and choice of parameters to assess regional ventricular function: The semiquantitative approach. Echocardiography 1990: Proceedings of the 7th international congress on echocardiography. ICS916; ; 1990. p. 365-8.

  85. Bullian PL, Zagonel V, Pinto A, Attadia V, Marotta G, Coglievina M, Lestuzzi C, et al. Phase I-II study of 5-aza-2'-deoxycytidine as a differentiation inducer in elderly patients affected by acute myeloid leukemia. Folia Oncologica. 1989;12(2):104-8.

  86. Moro E, D'Angelo G, Pandullo C, Nicolosi GL, Dall'Aglio V, Mimo R, et al. Apical hypertrophic cardiomyopathy: Variability of  bidimensional echocardiographic and electrocardiographic expression. G Ital Cardiol. 1989;19(5):402-10.

  87. Lestuzzi C, Nicolosi GL, Biasi S, Piotti P, Zanuttini D. Sensitivity and specificity of electrocardiographic ST-T changes as markers of neoplastic myocardial infiltration: Echocardiographic correlation. Chest. 1989;95(5):980-5.

  88. Dall'Aglio V, Nicolosi GL, Burelli C, Zardo F, Pavan D, Lestuzzi C, et al. Echocardiographic findings of left ventricular hypertrophy and normalization of parameters of left ventricular function in patients with previous evidence of dilated and poorly contracting left ventricle and coexisting systemic hypertension. Clin Cardiol. 1989;12(2):91-6.

  89. Lestuzzi C, Nicolosi GL, Moro E, Zanuttini D. Two-dimensional and doppler echocardiographic documentation of appearance and progression of carcinoid heart disease. Echocardiography. 1988;5(4):247-51.

  90. Errante D, Zagonel V, Lestuzzi C, Freschi A, Saracchini S, Tirelli U. Phase II study with 4-demethoxydaunorubicin per os in elderly patients affected by non hodgkin lymphoma and multiple myeloma. Folia Oncologica. 1988;11(2):214-8.

  91.  Nicolosi GL, Lestuzzi C, Pavan D, Dall'Aglio V, Mimo R, Breda M, et al. Qualitative ultrasonic tissue characterization of the myocardium. J Nucl Med Allied Sci. 1988;32(3):139-48.

  92. Moro E, Pignoni P, Nicolosi GL, Dall'Aglio V, Sparacino L, Pavan D, et al. Normally functioning mitral prosthesis: Visualization and characterization of the trans-valvular flow using color-coded doppler. G Ital Cardiol. 1988;18(3):198-205.

  93. Figoli F, Zanette ML, Tirelli U, Sorio R, Lestuzzi C, Urso R, et al. Pharmacokinetics of VM 26 given intrapericardially or intravenously in patients with malignant pericardial effusion. Cancer Chemother Pharmacol. 1987;20(3):239-42.

  94. Moro E, Nicolosi GL, Pignoni P, Pavan D, Dall'Aglio V, D'Angelo G, et al. Visualization and characterization of the transvalvular jet in mitral stenosis using color-coded doppler. G Ital Cardiol. 1987;17(10):815-22.

  95. Zerio C, Nicolosi GL, Burelli C, Lestuzzi C, Pavan D, Zardo F, et al. Heterogeneity of left ventricular wall dynamics in normal hearts and in chronic aortic regurgitation. A two-dimensional echocardiographic study. G Ital Cardiol. 1987;17(5):437-43.

  96. Pavan D, Nicolosi GL, Lestuzzi C. Normalization of variables of left ventricular function in patients with alcoholic cardiomyopathy after cessation of excessive alcohol intake: An echocardiographic study. Eur Heart J. 1987;8(5):535-40.

  97. Lestuzzi C, Nicolosi GL, Marin MG. Abnormal myocardial texture demonstrated by ultrasound in two patients with idiopathic haemochromatosis. Eur Heart J. 1987;8(6):630-3.

  98. Lestuzzi C, Biasi S, Nicolosi GL. Secondary neoplastic infiltration of the myocardium diagnosed by two-dimensional echocardiography in seven cases with anatomic confirmation. J Am Coll Cardiol. 1987;9(2):439-45.

  99.  Pavan D, Nicolosi GL, Lestuzzi C. Qualitative tissue characterization of fresh cardiac thrombi by two-dimensional echocardiography. Journal of Cardiovascular Ultrasonography. 1986;5(4):341-5.

  100. De Piccoli B, Nicolosi GL, Piccolo E, Franceschi M, Zerio C, Cervesato E, et al. Electrocardiographic changes and echocardiography variations in ventricular morphology in left ventricular overload. G Ital Cardiol. 1986;16(10):810-7.

  101. Dall'Aglio V, Nicolosi GL, Burelli C, Zardo F, Pavan D, Lestuzzi C, et al. Value and limitations of the echocardiographic definition of the bicuspid aortic valve. G Ital Cardiol. 1986;16(2):155-61.

  102. Nicolosi GL, Pavan D, Burelli C, Dall'Aglio V, Lestuzzi C, Zardo F, et al. Study of the intracardiac flow by real-time bidimensional color-coded doppler echocardiography. preliminary experience. G Ital Cardiol. 1986;16(1):38-44.

  103. Lestuzzi C, Nicolosi GL, Pavan D. Neoplastic infiltration of the myocardium: In vivo diagnosis and follow-up by two-dimensional echocardiography. Journal of Cardiovascular Ultrasonography. 1985;4(1):55-9.

  104. Dall'Aglio V, Nicolosi GL, Burelli C, Zardo F, Pavan D, Lestuzzi C, et al. Possibilities and difficulties of differential diagnosis by 2-dimensional echocardiography of mobile masses inside the right atrium. apropos of a case. G Ital Cardiol. 1985;15(8):812-5.

  105. Dall'Aglio V, Nicolosi GL, Burelli C, Zardo F, Pavan D, Lestuzzi C, et al. Role of bidimensional echocardiography in the study of aneurysms of a membranous septum associated with defects of the intraventricular septum of perimembranous type. G Ital Cardiol. 1985;15(4):392-9.

  106. Lestuzzi C, Nicolosi GL, Pavan D. Value of 2-D echocardiography in the diagnosis of pericardial diseases. new perspectives of differential diagnosis. G Ital Cardiol. 1985;15(3):310-8.

  107. Nicolosi GL, Pavan D, Lestuzzi C, Burelli C, Zardo F, Zerio C, et al. In: Qualitative tissue characterization of fresh cardiac thrombi by two-dimensional echocardiography in vitro and in vivo. Proceedings of the annual meeting of the American Institute of Ultrasound in Medicine; ; 1984. p. 212.

  108.  Pavan D, Nicolosi GL, Lestuzzi C. In vivo and in vitro evaluation of left ventricular thrombi by two-dimensional echocardiography. comparison with cineventriculography. G Ital Cardiol. 1984;14(7):471-8.

  109. Nicolosi GL, Pavan D, Lestuzzi C. Prospective identification of patients with amyloid heart disease by two-dimensional echocardiography. Circulation. 1984;70(3 I):432-7.

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